Technology and laboratory
Vivabioma™
Our Reference Laboratory
Our analytical processing takes place at Eurofins Genomics Denmark, one of the few centers in Europe with the technological capacity to handle the high volume of microbiome samples we process monthly. We work in close collaboration with their state-of-the-art facilities to exclusively perform shotgun metagenomic sequencing (WGS) on your samples. As a European leader in genomics, this laboratory operates under a rigorous quality framework. It holds top-level certifications that guarantee excellence, traceability, and maximum precision in every step of the extraction and sequencing of your microbial DNA:
- ISO 17025: International accreditation for analytical excellence in laboratory testing.
- ISO 13485: Compliance with the strictest standards for medical devices and products.
- ISO 15189: Global standard for quality and technical competence specific to medical laboratories.
- GLP (Good Laboratory Practice): The gold standard ensuring reliability in non-clinical safety studies.
- GCP (Good Clinical Practice): Quality assurance in genomics services applied to clinical studies.
- cGMP (Current Good Manufacturing Practice): Production and testing fully aligned with the strict requirements of the pharmaceutical and biotechnology industries.
Technology: Shotgun Metagenomic Sequencing
Always at the forefront of scientific innovation, at Vivabioma we stay up to date with the most advanced technologies in microbiota DNA sequencing. With our comprehensive analysis, we process 80 million reads per sample, far exceeding traditional techniques (such as 16S sequencing), which are limited to detecting only a part of the bacteria. This process does not only focus on the main bacterial groups but also detects microorganisms that usually go unnoticed in conventional analyses, covering bacteria, archaea, fungi, and viruses. To guarantee maximum precision and reliability, we employ this massive depth based on industry-leading technology, which means we capture the genetic material of your entire intestinal community with extraordinary resolution, minimizing errors and confirming results with the highest possible accuracy.
Full profiling of microorganisms and functional pathways
Unlike other more restricted intestinal analyses, Vivabioma identifies and characterizes the entire ecosystem. We evaluate everything from taxonomic assignment (who is there) to functional profiling (what they are doing). This includes the detection of key species and the abundance of vital metabolic pathways, such as the production of short-chain fatty acids (butyrate, acetate, and propionate) or vitamin synthesis. We understand the complexity of this data, so we offer clear results and personalized support to interpret them in a simple and applicable way.
Systematic and experienced work
As experts in metagenomics, we collaborate with reference laboratories and use international standard bioinformatic software to deliver excellent results. This comprehensive approach ensures that every step of the process, from DNA extraction to data cross-referencing, meets the most rigorous clinical quality standards.
Safe and reliable results
Vivabioma's analysis processes a staggering 80 million DNA reads per sample. Imagine taking a high-resolution panoramic photograph of an entire forest where you can zoom in to see the detail of every leaf: this massive depth allows us to detect even the least abundant microorganisms with total clarity. This reduces the margin of error to extremely low levels, offering you results you can fully trust to make informed decisions about your nutrition, well-being, and digestive health.
